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Infectious Disease: COVID-19

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Rapid genome-wide sequence typing of African swine fever virus based on alleles
Virus Res. 2021 Mar 2:198357. doi: 10.1016/j.virusres.2021.198357. Online ahead of print.ABSTRACTRapid and accurate molecular typing of African swine fever virus (ASFV) during outbreaks is important to reveal diversity and sourcing of ASFV. Here we present a new way to perform rapid genome-wide multi-locus sequence typing of ASFV using an allele calling based on gene by gene approach. Using open-accessed chewBBACA software, 41 publicly available ASFV genomes were analyzed to optimize the parameters to find the alleles. Alleles as many as 127 were found for building the phylogenetic trees, which covered more than 60% of the...
Source: Virus Research - March 5, 2021 Category: Virology Authors: Dongyan Xiong Xiaoxu Zhang Jin Xiong Junping Yu Hongping Wei Source Type: research

Swine enteric alphacoronavirus (swine acute diarrhea syndrome coronavirus): an update three years after its discovery.
Abstract Discovered in 2017, swine enteric alphacoronavirus (SeACoV), also known as swine acute diarrhea syndrome coronavirus (SADS-CoV) or porcine enteric alphacoronavirus (PEAV), is the fifth porcine CoV identified in diarrheal piglets. The presumed name "SADS-CoV" may not be appropriate since current studies have not provided strong evidence for high pathogenicity of the virus. SeACoV was the most recently recognized CoV of potential bat origin prior to the novel human severe acute respiratory syndrome CoV 2 (SARS-CoV-2), associated with the pandemic CoV disease 2019 (COVID-19). Although SeACoV is recognized as...
Source: Virus Research - May 15, 2020 Category: Virology Authors: Yang YL, Yu JQ, Huang YW Tags: Virus Res Source Type: research

Identification and epitope mapping of swine acute diarrhea syndrome coronavirus accessory protein NS7a via monoclonal antibodies
Virus Res. 2022 Mar 10:198742. doi: 10.1016/j.virusres.2022.198742. Online ahead of print.ABSTRACTSwine acute diarrhea syndrome coronavirus (SADS-CoV) is an emerging swine enteric coronavirus that causes vomiting, severe diarrhea, dehydration and death in suckling piglets. NS7a is putative accessory protein that is predicted to be encoded by SADS-CoV, but still to be confirmed experimentally. In the present study, recombinant NS7a protein was expressed in a prokaryotic expression system and used as an antigen to prepare monoclonal antibodies (mAbs) specific to NS7a protein. We obtained two anti-NS7a mAbs, termed AH5 and EH...
Source: Virus Research - March 14, 2022 Category: Virology Authors: Yibin Qin Tingshuai Feng Hongyan Shi Jiyu Zhang Liaoyuan Zhang Shufeng Feng Jianfei Chen Ying He Xin Zhang Zhongwei Chen Jianbo Liu Dakai Liu Da Shi Li Feng Source Type: research

Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns
Vet Q. 2022 May 18:1-39. doi: 10.1080/01652176.2022.2079756. Online ahead of print.ABSTRACTSwine coronaviruses (SCoVs) are one of the most devastating pathogens affecting the livelihoods of farmers and swine industry across the world. These include transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine respiratory coronavirus (PRCV), porcine hemagglutinating encephalomyelitis virus (PHEV), swine acute diarrhea syndrome coronavirus (SADS-CoV), and porcine delta coronavirus (PDCoV). Coronaviruses infect a wide variety of animal species and humans because these are having single stranded-R...
Source: Veterinary Quarterly - May 18, 2022 Category: Veterinary Research Authors: Jigarji C Thakor Murali Dinesh Rajendran Manikandan Suresh Bindu Monalisa Sahoo Diptimayee Sahoo Manish Dhawan Megha Katare Pandey Ruchi Tiwari Talha Bin Emran Kuldeep Dhama Wanpen Chaicumpa Source Type: research